摘要
目的总结青少年分化型甲状腺癌的诊治经验。方法回顾性分析我院1983年至2000年青少年分化型甲状腺癌的临床资料及随访结果。结果全组均行手术治疗辅以内分泌治疗,76例青少年分化型甲状腺癌中,病理示乳头状癌66例(86.8%),滤泡状腺癌10例(13.2%)。淋巴结转移者46例(60.5%)。手术方式包括单侧病变行患侧腺叶加峡部及对侧大部切除45例(其中行功能性颈清扫术42例),患侧腺叶加峡部切除12例(其中行患侧功能性颈清扫术10例);双侧病变行一侧腺叶+峡部及对侧大部切除加双侧功能性颈清扫术10例,甲状腺全切术加双侧颈清扫术9例(其中3例一侧功能性清扫、另一侧根治性清扫);2例肺转移患者行甲状腺全切及颈部淋巴结清扫术后行131I内放射治疗。74例获得随访,随访5～14年,中位随访时间7.8年,其中6例获得10年以上随访,5年生存率97.3%,10年生存率83.3%。结论青少年分化型甲状腺癌预后较佳,治疗的关键是正确根据其病情选择合适的手术方式。
Objective To summary the experience in diagnosis and surgical treatment of differentiated thyroid carcinoma （DTC） of adolescents. Methods The clinical data and follow- up resuits of 76 cases of DTC of adolescents were retrospectively analysed. Results 76 patients received operation and TSH suppress therapy. Histologic examination after operation revealed that papiUary thyroid carcinoma （PTC） 66 cases （86.8 % ）, follicular thyroid carcinoma 10 cases（ 13.2 % ）, cervical lymph node metastasis were found in 46 cases（60.5 % ）. The operation procedure consists of excision of the suffered lobe, isthmus and greater partial of the opposite lobe 45 cases （along with functional cervical dissection 42 cases） ;excision of the suffered lobe, isthmus 12 cases （along with functional cervical direction 10 cases） ; total thyroideetomy and bilateral cervical dissection 9 cases; all 76 received postoperative thyroid hormone suppressive therapy. The follow - up period was 5 to 14 years, and the 5 - and 10 - year survival rate were 97.3 % and 83.3 %. Conclusion Differentiated thyroid carcinoma of adolescents has a good prognosis, a proper surgical procedure is the key point to get a good outcome.
出处
《临床外科杂志》
2006年第3期142-144,共3页
Journal of Clinical Surgery
关键词
青少年
分化型甲状腺癌
诊断
治疗
adolescent
differentiated thyroid carcinoma
diagnosis
treatment
