摘要
目的探讨SENSE技术支持下磁共振扩散成像ADC值在诊断肝硬化和肝癌中的应用价值。方法对30例正常健康志愿者、30例肝硬化、30例肝癌进行上腹部磁共振扩散加权成像扫描,在ADC图上直接测量其ADC值。结果在b值为300、1000和1500s/mm2时,正常肝脏ADC值范围分别为(1.520±0.169),(1.200±0.132),(1.068±0.118)×10-3mm2/s;肝硬化ADC值范围分别为(1.305±0.1181),(1.137±0.124),(1.006±0.107)×10-3mm2/s;肝癌ADC值范围分别为(1.163±0.206),(0.898±0.155),(0.803±0.140)×10-3mm2/s。经统计学分析其存在明显统计学差异(P<0.05)。结论磁共振扩散成像ADC值在肝硬化和肝癌的诊断中有一定价值。
Objective To evaluate the diagnostic value of apparent diffusion coefficient （ADC） values in liver cirrhosis and hepatocellular carcinoma by using SENSE technique. Methods Diffusion weighted imaging （DWI） was performed in 30 healthy volunteers, 30 hepatocellular carcinoma and 30 liver cirrhosis. All data were acquired by using PHILIPS software on the ADC imaging. Results The DWI and ADC imaging were successfully acquired from all healthy control and 60 patients. When b values were 300, 1000, 1500 s/mm^2 respectively, the ADC values of normal liver, cirrhotic liver, and hepatocellular carcinoma were （1. 520±0. 169）, （1. 200±0. 132）, （1. 068±0. 118） × 10^-3mm^2/s; （1. 305±0. 1181）, （1. 137±0. 124）, （1. 006±0. 107） × 10^-3mm^2/s; （1. 163±0. 206）, （0. 898±0. 155）, （0. 803~0. 140） ×10^-3mm^2/s, respectively. The ADC values of the same organ showed significant differences under different b values （P〈0.05）, and the ADC values of three different groups showed significant differences under the same b value （P〈0.05）. Conclusion The ADC value plays an important role in the diagnosis of hepatocellular carcinoma and liver cirrhosis.
出处
《中国医学影像技术》
CSCD
北大核心
2006年第3期423-425,共3页
Chinese Journal of Medical Imaging Technology
基金
陕西省科技攻关项目(2004k12G10)。
关键词
表观扩散系数
磁共振成像
肝细胞癌
肝硬化
Apparent diffusion eoeffieient
Magnetic resonance imaging
Hepatoeellular eareinoma
Liver cirrhosis
