摘要
目的:探讨磁共振扩散加权成像(DWI)在肝脏占位性病变中的应用价值。方法:对30例无肝脏病变者的正常肝组织及105例164个肝占位性病灶(肝囊肿22例40个病灶,肝血管瘤37例40个病灶,肝细胞癌23例32个病灶,肝转移瘤15例35个病灶,肝脓肿8例17个病灶)行DWI,并测量表观扩散系数值(ADC值)。结果:正常肝组织的ADC值为(1.42±0.08)×10-3mm2/s。肝囊肿、肝血管瘤、肝细胞癌、肝转移瘤及肝脓肿的ADC值分别为(4.33±0.25)×10-3、(2.43±0.25)×10-3、(1.63±0.08)×10-3、(1.78±0.07)×10-3、(1.18±0.11)×10-3mm2/s,各组之间差异均存在统计学意义(P<0.01)。结论:分析DWI及测量ADC值对肝脏占位性病变的鉴别诊断有一定价值,有利于小病灶的显示,可作为肝脏MRI检查的常规序列之一,但不利于小病灶的定性诊断。
Objective: To evaluate the application of diffusion-weighted MR imaging in liver focal masses. Methods: Diffusion-weighted MR imaging(DWI) and measurement of apparent diffusion coefficient(ADC) were performed in 30 normal cases and 105 patients with 164 liver focal masses(liver cyst 40,liver hemangioma 40, hepatocellular carcinoma 32, liver metastasis 35 and liver abscess 17). Result: The mean ADC value of normal liver is(1.42±0.08)×10 -3 mm\+2/s. Distinctive ADC values were found in liver lesions. ADCs in patients with hepatic disease included liver cysts,(4.33±0.25)×10 -3 mm\+2/s; liver hemangiomas, (2.43±0.25)×10 -3 mm\+2/s; hepatocellular carcinoma, (1.63±0.08)×10 -3 mm\+2/s; liver metastasis, (1.78±0.07)×10 -3 mm\+2/s; and liver abscess,(1.18± 0.11 )×10 -3 mm\+2/s. The difference between the mean ADC values was significant (P<0.01). Conclusion: Diffusion-weighted MR imaging is useful in differentiated diagnosis of liver focal masses and advantage to show of small lesions. It can be one of the routine sequence in the examination,however, it is not promising to qualitative analysis for small liver lesions.
出处
《新疆医科大学学报》
CAS
2005年第5期475-477,共3页
Journal of Xinjiang Medical University
关键词
肝肿瘤
磁共振扩散加权成像
磁共振
hepatic neoplasm
diffusion-weighted MR imaging
magnetic resonance
