摘要
目的探讨女性膀胱过度活动症(OAB)和OAB合并压力性尿失禁(OAB+SUI)患者尿动力表现。方法有OAB症状的女性患者76例,依据患者病史和主诉分为2组,Ⅰ组为单纯OAB患者(n=38,年龄(53±8)岁),Ⅱ组为OAB合并SUI患者(n=38,年龄(57±12)岁)。比较2组尿动力学参数。结果OAB组初始尿意容量,强烈排尿感容量、最大膀胱测压容量均小于OAB+SUI组(P<0.05),而最大尿道压、最大尿道闭合压和功能性尿道长度均大于OAB+SUI组(P<0.05);OAB组中真性压力性尿失禁(GSI)2例(5%)、逼尿肌过度活跃(DO)26例(68%)、DO合并GSI2例(5%)和正常8例(22%),而OAB+SUI组则分别有23例(61%)、8例(21%)、4例(10%)和3例(8%),2组在GSI和DO例数上有明显差异(P<0.05)。结论尿动力学结果显示女性OAB合并SUI患者较单纯OAB患者尿道压力低。尿动力学检查可明确其是否伴有其他膀胱功能障碍,为OAB的临床诊断和治疗提供帮助。
Aim ： To investigate the urodynamic changes in female overactive bladder （OAB） with or without stress urinary incontinence （SUI）. Methods：According to history and complaints, 76 cases were divided into 2 groups. Group Ⅰ was OAB （n = 38 ）, Group Ⅱ was OAB ＋ SUI. The urodynamic results were compared between two groups. Results： First desire to void, strong desire to void and maximum cystometric capacity in group Ⅰ were significantly lower than those in group Ⅱ （ P 〈 0.05 ） ; maximal urethral pressure, maximal urethral closure pressure and functional urethral length in group Ⅱ were significantly lower than those in group Ⅰ （P 〈 0.05 ） ; Additionally, 2 cases（ 5% ） had genuine stress incontinence （GSI） , 26 cases（68% ） had detrusor overactivity（DO） , 2 cases （5%） had GSI plus DO in group Ⅰ , and these in group Ⅱ were observed in 23 cases （61%） ,8 cases （21%） and 4 cases （ 10% ） , respectively. The percentage of GSI and DO had significant difference between the 2 groups （ P 〈 0.05 ）. Conclusion ： Patients with OAB ＋ SUI have lower urethral pressure than that of patients simply with OAB. Urodynamic test can be used to identify the coexistent bladder dysfunction for patients with OAB.
出处
《郑州大学学报（医学版）》
CAS
北大核心
2006年第2期210-212,共3页
Journal of Zhengzhou University(Medical Sciences)
基金
国家自然科学基金资助项目30571931
河南省杰出青年科学基金02120001100
河南省高校杰出科研人才创新工程项目2001KYCX004
河南省高等学校创新人才培养工程2002-2007
