摘要
目的探讨CA125、CA153联合检测对诊断子宫内膜癌的临床意义。方法36例经病理检查证实为子宫内膜癌的患者于入院时和手术后2～3个月进行CA125、CA153联合检测，以同期住院行剖腹手术、经病理证实为子宫肌瘤患者57例作为对照组。结果两项指标同时检测较单项检测对辅助诊断子宫内膜癌的敏感性提高到82．3％，虽特异性有所下降，但总的准确性提高到75．1％，与子宫肌瘤对照组比较，有统计学意义（P〈0．05）。结论两项肿瘤标志物联合检测，相互补充，对鉴别子宫良、恶性疾病和判断预后及复发有重大的诊断意义。
Objective To study the clinical value of combined detection of CA125 and CA153 for diagnosis of endometrial carcinoma. Methods The combimed detection of CA125 and CA153 were performed in 36 patients with endometrial carcinoma,confirmed by pathological examination,on admission and 2-3 months after operation. Fifty-seven patients with uterine myoma,admitted for laparotomy in the same period and confirmed by pathology,were as controls. Results The sensitivity of combined detection of CA125 and CA153 for diagnosing endometrial carcinoma increased to 82.3% and the specificity decreased. Total accuracy rate of diagnosis reached 75.1%. There was statistical difference between the group of endometrial carcinoma and controls（P〈0.05）. Conclusion The combined detection of two tumor makers has the important diagnostic value for differentiating benign and malignant diseases of uterus,judging prognosis and recurrence.
出处
《国际检验医学杂志》
CAS
2006年第3期222-223,共2页
International Journal of Laboratory Medicine
