摘要
目的观察异痛消对子宫内膜异位症的疗效及患者血浆CA125水平变化。方法对符合诊断标准的181例子宫内膜异位症患者,采用随机数字表法将患者分为治疗组(异痛消胶囊组)90例、中药对照组(散结镇痛胶囊组)60例、西药对照组(芬必得胶囊组)31例,治疗前后在卵泡期的相同时间于上午10时前取空腹静脉血3 mL抗凝,并对其血浆CA125水平进行测定。结果中医症候疗效比较:治疗组总有效率(97.14%),中药对照组(91.43%),西药对照组(34.29%)。治疗后患者血浆CA125水平均有下降,其中治疗组与中药对照组下降明显,与治疗前比较有显著差异(P<0.01),西药对照组与治疗前比较(P>0.05),无统计学意义。结论中药异痛消治疗子宫内膜异位症疗效良好,且明显降低患者血浆CA125水平。
Objective To investigate the influence of Yitongxiao on serum CA125 level in endometriosis pa- tients. Methods 181 cases of endometriosis were recruited. They were divided into 3 groups, treatment group （90 cases ） and control group of Sanjiezhentong （ 60 cases）, control group of Fenbid （ 31 cases） respectively for 3 months. The clinical symptoms and serum CA125 level was observed and recorded before and after treatment. Results The total effective rate was 97. 14% in treatment group and 91.43% in control group of Sanjiezhentong, and 34. 29% in control group of Fenbid. The serum CA125 decreased in all groups. There was significant difference between treatment group and control group of Sanjiezhentong （ P 〈 0. 01 ）. And there was no significant difference between treatment group and control group of Fenbid （ P 〉 0. 05 ）. Conclusions Yitongxiao can significant improve the clinical symptoms of endometriosis, and can significantly decrease the serum CA125 level.
出处
《航空航天医学杂志》
2014年第1期1-4,共4页
Journal of Aerospace medicine
