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非小细胞肺癌患者EGFR突变和基因扩增对吉非替尼疗效的预测价值 被引量：2

The Value of EGFR Mutation and Gene Amplification in Predicting Response to Gefitinib in NSCLC Patients
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摘要 1文献类型 治疗。 2证据水平 1b；杂志影响因子：9．835。 3文献来源 Bell DW, Lynch TJ, Haserlat SM, et al. Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer： molecular analysis of the IDEAL/INTACT gefitinib trials [J]. J Clin Oncol, 2005, 23（31） ： 8081-8092.
作者 李龙芸 周彩存 张国淳
机构地区 中国医学科学院北京协和医院呼吸科 上海市肺科医院肿瘤科 广东省人民医院肿瘤中心
出处 《循证医学》 CSCD 2006年第1期23-27,共5页 The Journal of Evidence-Based Medicine
关键词 癌 非小细胞肺 药物治疗 突变 基因扩增 预测 carcinoma, non-small-cell lung drug therapy mutation gene amplification forecasting
分类号 R734.2 [医药卫生—肿瘤]
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参考文献9

  • 1Paez JG,Janne PA,Lee JC,et al.EGFR mutations in lung cancer:correlation with clinical response to gefitinib therapy[J].Science,2004,304:1497-1500. 被引量：1
  • 2Lynch TJ,Bell DW,Sordella R,et al.Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib[J].N Engl J Med,2004,350:2129-2139. 被引量：1
  • 3Mu XL,Li LY,Zhang XT,et al.Evaluation of safety and efficacy of gefitinib (‘iressa',ZD1839) as monotherapy in a series of Chinese patients with advanced non-small-cell lung cancer:experience form a compassionate-use programme[J].BMC Cancer,2004,4:51-59. 被引量：1
  • 4Mu XL,Li LY,Zhang XT,et al.Gefitinib-sensitive mutations of the epidermal growth factor receptor tyrosine kinase domain in chinese patients with non-small cell lung cancer[J].Clin Cancer Ras,2005,11(12):4289-4294. 被引量：1
  • 5Bell DW,Lynch TJ,Haserlat SM,et al.Epidermal growth factor receptor mutation and gene amplification in non-smallcell lung cancer:molecular analysis of the IDEAL/INTACT gefitinib trials[J].J Clin Oncol,2005,23(31):8081-8092. 被引量：1
  • 6Parra HS,Cavina R,Latteri F,et al.Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib (‘ Iressa',ZD1839)in non-small-cell lung cancer[J].Br J Cancer,2004,91:208-212. 被引量：1
  • 7Pao W,Miller V,Zakowski M,et al.EGF receptor gene mutations are common in lung cancers from "never smokers"and are associated with sensitivity of tumors to gefitinib and erlotinib[J].Proc Natl Acad Sci USA,2004,101:13306-13311. 被引量：1
  • 8Huang SF,Liu HP,Li LH,et al.High frequency of epidermal growth factor receptor mutations with complex patterns in nonsmall cell lung cancers related to gefitinib responsiveness in Taiwan[J].Clin Cancer Res,2004,10:8195-8203. 被引量：1
  • 9Kosaka T,Yatabe Y,Endoh H,et al.Mutations of the epidermal growth factor receptor gene in lung cancer:biological and clinical implications[J].Cancer Res,2004,64:8919-8923. 被引量：1

同被引文献13

  • 1陈智伟,廖美琳.RECIST标准在肿瘤治疗疗效评价中的应用[J].中国肿瘤,2004,13(10):616-618. 被引量：175
  • 2常涛,梅丹,张力,李大魁.新型抗肿瘤药物——吉非替尼[J].中国药学杂志,2006,41(12):958-959. 被引量：16
  • 3Dy GK, Adjei AA. Novel targets for lung cancer therapy [J]. Part I J Clin Oncol, 2002,20 : 2881-2894. 被引量：1
  • 4Buun PA Jr,Kelly K. New chemotherapeutic agents prolong survival and improve quality of life in non-small cell lung cancer:a review of the literature and future directions [J ]. Clin Cancer Res, 1998.4:1087-1100. 被引量：1
  • 5Barton J, Blackledge G,Wakeling A. Growth factors and their receptor:new targets for prostate cancer therapy[J]. Urology,2001, 58(2 Suppl 1):114-122. 被引量：1
  • 6Ciardiello F,Caputo R,Bianco R,et al. Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (lressa) ,a selective epidermal growlh factor receptor tyrosine kinase inhibitor[J ]. Clin Cancer Res,2001,7: 1459-1465. 被引量：1
  • 7Giaccone G,Herbst RS,Manegold C,et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer :a phase Ⅲ trial-INTACT 1 [ J ]. J Clin Oncol,2004,22 : 777-754. 被引量：1
  • 8Herbst RS,Giaccone G,Schiller JH,et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer : a phase Ⅲ trial-INTACT 2 [ J ]. J Clin Oncol,2004,22 : 785-794. 被引量：1
  • 9Birnbaum A ,Ready N. Gefitinib therapy for non-small cell lung cancer [ J ]. Curr Treat Options Oncol, 2005,6 : 75-81. 被引量：1
  • 10Cohen MH,Williams GA,Sridhara R,et al. FDA drug approval Summary : gefitinib (ZD 1839) (lressa) tablets [ J ]. Oncologist, 2003, 8 : 303-306. 被引量：1

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二级引证文献11

循证医学
2006年 第1期

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