摘要
目的:探讨晚发支气管哮喘与老年COPD患者气道反应性等呼吸功能特点。方法:36例晚发支气管哮喘与58例老年COPD行通气功能,气道阻力,肺气肿分度及气道反应性比较。结果:缓解期晚发支气管哮喘97%存在气道高反应性(BHR),而COPD组BHR仅为12%,且乙酰甲胆碱浓度为哮喘组的4·8倍(P<0·005),COPD组V25下降达100%,且气道阻力在激发前后无明显改变,肺气肿分度以中重度为主。结论:COPD组小气道损害及肺气肿程度较重,而气道高反应性测定对于老年哮喘患者检出较为敏感,并对差异的可能机理进行了探讨。
Objective： To detect the charaeterization of Bronchial Reactivity and other pulmonary funetiorts in elderly patients with late asthma and COPD.Method： Complicated the ventilafive function, Raw, the degrees of pulmonary enphysemea and Bronchial Reactivity in both groups. Results： BHR in aged Asthma is 97% and in COPD is 12%. The concentration of Meh in COPD is 4.8 times higher than in aged As thma. V25 decrease are 100% in group and the Raw are not changed after challenge test. The degrees of pulmonary enphysema are much severe than in aged as thma. Conclusions： The destruction of little airway and the degree of pulmonary enphysema are much severe in COPD. The Test of Bronchial Reactivity is more sensitive to astma.
出处
《华西医学》
CAS
2006年第1期34-35,共2页
West China Medical Journal
