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白细胞介素10在系统性红斑狼疮发病机制中的意义 被引量:3

The Significance of Interleukin-10 in the Pathogenesis of Systemic Lupus Erythematosus
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摘要 白细胞介素(IL)-10在系统性红斑狼疮(system ic lupus erythem atosus,SLE)患者体内异常升高,其基因与SLE易感性相关。它既是B细胞的刺激因子,又是Th1细胞的抑制因子,同时与SLE细胞凋亡异常有关,参与SLE的发病过程。在SLE的不同时期,它对炎症反应发挥着不同的效应。本文综述IL-10在系统性红斑狼疮发病机制中作用的最新研究进展,旨在阐明它在SLE发生发展中的重要作用和临床价值。
出处 《中国皮肤性病学杂志》 CAS 北大核心 2006年第2期112-114,共3页 The Chinese Journal of Dermatovenereology
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