摘要
目的探讨含眼科十四号中药血清对不同条件诱导的牛视网膜血管内皮细胞(BREC)增殖的影响。方法用MTT法检测含眼科十四号鼠血清对建立的慢性缺氧条件和bFGF刺激下BREC的增殖变化。结果含眼科十四号鼠血清对不同条件下培养BREC均有明显抑制作用,其抑制率呈量效和时效关系。结论含眼科十四号鼠血清对慢性缺氧和bFGF刺激下BREC的增殖有明显抑制作用。为中药复方治疗视网膜新生血管形成提供参考。
OBJECTIVE To study the effect of herbal medicines serum on the effect of BREC induced by different conditions. METHODS Through MTT method check up the effect of Yankeshisihao （眼科十四号） on the proliferation of BREC stimulated by chronic hypoxia or bFGF. RESULTS The serum can restrain the proliferation of BREC induced by chronic hypoxia or bFGF greatly, the rate is enhanced along with time and dose. CONCLUSIONS The herbal medicines serum of Yankeshisihao can restrain the proliferation of BREC induced by hypoxia or bFGF greatly, which can prove that the herbal is useful of retinal neovascularization.
出处
《中国中医眼科杂志》
2006年第1期41-42,共2页
China Journal of Chinese Ophthalmology
