摘要
目的:探讨青霉素类药物致泌尿系统不良反应的一般规律及特点。方法:对近年来国内公开发表的有关青霉素类药物致泌尿系统不良反应文献进行整理、分析。结果:不良反应病例共57例,包括急性肾功能衰竭12例、血尿3例、尿蛋白异常29例、尿崩症和尿潴留5例、肾绞痛3例、急性间质性肾炎5例。结论:临床应重视青霉素类药物可致泌尿系统的不良反应,确保用药安全。
OBJECTIVE： To discuss the adverse drug reactions（ADRs） of penicillin in urinary system.METHODS： The recent reported eases home and abroad of ADRs of penicillin in urinary system were collected and analyzed.RESULTS：Among the 57 cases of ADRs, there were 12 cases of acute renal failure, 3 cases of hematuria, 29 cases of abnormal urinal protein, 5 cases of diabetes insipidus and retention of urine, 3 cases of renal angina and 5 cases of acute interstitial nephritis,CONCLUSIONS： Great importance should be attached to the ADRs of penicillin in urinary system in clinic in order to ensure the safety of drug use.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第4期290-292,共3页
China Pharmacy
关键词
青霉素
泌尿系统
不良反应
分析
Penicillin
Urinary system
Adverse drug reaction
Analysis
