摘要
目的探讨胡桃楸提物对常见深部感染真菌生长的抑制作用。方法以NCCLS方案检测胡桃楸提取物和伊曲康唑(ICZ)、氟康唑(FCZ)、两性霉素B(AMB)和5-氟胞嘧啶(5-FC)对白念珠菌、新生隐球菌和烟曲霉菌体外最小抑菌浓度(MIC)和最小杀菌浓度(MFC)。结果胡桃楸提取物对深部致病性真菌有较强的抑菌和杀菌作用,其作用强度与ICZ、FCZ相当,但逊色于AMB和5-FC。结论胡桃楸提取物对深部致病性真菌体外生长有较强的抑菌和杀菌作用。
Objective To explore antifungal activity in vitro of extracts of Juglans on deep - seated infectious fungi. Methods Minimal inhibitory concentration （MIC） and minimal fungicidal concentration （MFC） in vitro of extracts of Juglans, Itraconazole （ICZ）, Fluconazole （FCZ）, Amphotericin B （AMB） and Flucytosine （ 5 - FU） on Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus were detected by NCCLS way, Results MIC and MFC in vitro of extracts of Juglans on Candida albicans, Cryptococcus neoforrnans and Aspergillus fumigatus was similar to ICZ and FCZ, but lower than AMB and 5 - FU. Conclusions Extracts of Juglans can inhibit the growth of deep - seated infectious fungi significantly in vitro.
出处
《实用全科医学》
2006年第1期94-94,共1页
Applied Journal Of General Practice
关键词
胡桃楸
白色念珠菌
新生隐球菌
烟曲霉菌
生长
抑制作用
Juglans
Candida albicans
Cryptococcus neoformans
Aspergillus fumigatus
Growth
Inhibition
