摘要
目的探讨急性一氧化碳(CO)中毒患者血清S100B蛋白浓度变化及其对预后的影响。方法用双抗体夹心(ELISA)法测定65例CO中毒患者和38例对照者血清S100B蛋白浓度,观察中毒人群36个小时内血清S100B蛋白浓度,了解S100B蛋白变化对预后的影响。结果①CO中毒患者血清S100B蛋白水平显著高于对照组(P<0.001);②S100B蛋白水平与预后严重程度显著相关。结论血清S100B蛋白浓度升高是CO中毒患者早期脑损伤的重要标记。
Objective To explore the prognostic value of SIOOB protein in the serum in patients with acute carbon monoxide poisoning. Methods 65 patients with acute carbon monoxide poisoning in test group and 38 in control group were measured for SIOOB protein in the serum by ELISA. Results OThe S100B protein of serum in test group and in control group were （1.01 ± 0.24）μg/L and （0.34 ± 0.19）ug/L,respoctively （P 〈 0.001 ） ;OThe leves of S100B protein of serum with acute carbon monoxide poisoning is related well to prognostic. Conclusion The S100B protein of serum is biochemical markers for brain damage after acute carbon monoxide poisoning.
出处
《四川医学》
CAS
2006年第1期40-41,共2页
Sichuan Medical Journal
关键词
CO中毒
脑损伤
S100B蛋白
血清
carbon monoxide poisoning
brain damage
S100B protein
serum
