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血清γ干扰素诱导蛋白-10、IL-8在初诊DM2中的表达及意义

The Expression and Significance of Serum IP-10 and IL-8 in Patients with Recently Diagnosed Type 2 Diabetes Mellitus
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摘要 目的:探讨炎症细胞因子γ干扰素诱导蛋白-10(IP-10)、白介素-8(IL-8)在2型糖尿病(DM2)患者中的表达及意义。方法:检测37例初诊DM2患者及健康人33例血清IP-10、IL-8浓度并予对照分析。结果:DM2组IP-10、IL-8浓度均显著高于健康人。结论:IP-10、IL-8在DM2发病中可能起一定作用。 Objective To investigate the significance of IL - 10 and IL - 8 in the pathogenesis of type2 diabetes mellitus (DM2). Methods The serum levels of IL - 10 and IL - 8 were measured in 37 patients with recently diagnosed type 2 diabetes mellitus and 33 controls. Results The serum levels of IL - 10 and IL - 8 patients with DM2 were significantly higher than those in controis (P 〈 0. 001 ). Conclusion The higher levels of IL - 10 and IL - 8 might play some role in the pathogenesis of DM2.
出处 《放射免疫学杂志》 CAS 2005年第6期462-463,共2页 Journal of Radioimmanology
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