摘要
目的:研究祁州漏芦Rhaponticum uniflorum根中的化学成分.方法:采用硅胶及Sephadex LH-20柱色谱进行分离纯化,通过理化性质和光谱分析鉴定结构.结果:从中分离得到了5个三萜类化合物,分别鉴定为乌索酸(1),3-氧-19α-羟基乌索-12-烯-28-酸(2),坡模堤酸(3),arjunic acid(4)和tormentic acid(5).结论:以上化合物1～5均为首次从该属植物中分得.
Objective： To study the chemical constituents of the root of Rhaponticum uniflorum. Method： Separation and purification were performed on silica gel and Sephadex LH-20 column chromatography. Their structure were elucidated on the basis of physicochemical and spectral analysis. Result： Five triterpenoid compounds were isolated and identified as ursolic acid （ 1 ）, 3-oxo-19a-hydroxyurs-12-en-28-oic acid （2）, pomolic acid （3）, arjunic acid （4） and tormentic acid （5）, respectively. Conclusion： Compounds 1 - 5 were isolated from the genus Rhaponticum for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2005年第23期1833-1836,共4页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(29772010)
福建省教育厅项目(K04054)
关键词
祁州漏芦
菊科
三萜
Rhaponticum uniflorum
Compositae
triterpenes
