摘要
目的观察马来酸曲美布汀联用双歧四联活菌对肠易激综合征(IBS)的疗效。方法85例IBS患者,随机分成2组:马来酸曲美布汀+双歧四联活菌组(治疗组A组)45例及复合维生素B+多酶片组(对照组B组)40例。马来酸曲美布汀0.1,每日三次,联用双歧四联活菌1.5,每日三次,治疗两周;复合维生素B 2片,每日三次,联用多酶片3片,每日三次,治疗两周。记录治疗前后症状和不良反应并进行评分。结果A组的总有效率93.3%,B组的总有效率22.5%,无1例严重的不良反应发生。A组与B组间存在显著性差异(P<0.005)。结论马来酸曲美布汀联用双歧四联活菌治疗IBS近期疗效确切,病人依从性好,值得推广应用。
Objective To observe the effect of the combination of Bifid Tetragenous Viable Bacteria Tablets and Trimebutine Maleate Capsules in treating the IBS. Methods 85 IBS patients were randomly divided into Group A and Group B;Group A was treated with Bifid Tetragenous Viable Bacteria Tablets （0.1g,Tid） and Trimebutine maleate Capsules （1.5g,Tid） ,while Group B was treated with VitBco Tablets （2^# ,Tid）, Diastase pancreatin and Pepsin Tablets （3^# , Tid） ;The treatment course of each group lasted for two weeks, the symptoms and ADR before and after treatment in both groups were recorded and were graded. Results The total effective rate in Group A was 93.3 % while that in Group B was 22.5 %, the difference was obvious （ P〈0.005 ）. Conclusions The treatment of the combination of BTVBT and TMC for IBS has exact effect and the patients can accept it easily, it is worthy of wide application.
出处
《西南军医》
2005年第6期8-9,共2页
Journal of Military Surgeon in Southwest China
