摘要
[目的]对常温与低温体外循环(CPB)在冠状动脉旁路移植术(CABG)中进行比较。[方法]80例冠状动脉搭桥手术患者,随机分为常温(膀胱温度37℃)组和低温(膀胱温度28℃)组,其他麻醉和CPB方法一致。将两组麻醉时间、手术时间、麻醉药用量、清醒时间、输液输血量及血糖统计学处理。[结果]两组芬太尼、潘库溴胺用量相近,而咪唑安定的用量在低温组明显多于常温组(P<0.05)。常温组自动复跳例数明显多于低温组,低心排综合征发生例数明显少于低温组(P<0.05)。从CPB开始直至入ICU3h两组血糖均明显高于麻醉前(P<0.05),且在CPB中、CPB停机时、手术结束时、入ICU3h低温组的血糖高于常温组(P<0.05)。胰岛素用量低温组多于常温组(P<0.05)。[结论]常温CPB简便易行,CPB时间短,对心脏无不良影响;且对周身器官干扰小,恢复快,避免了低温对机体的危害。
[ Objective] To compare the difference between normothersia CPB and hypothermia CPB in CABG surgeries. [ Methods] Eighty patients undergoing CABG were divided into normothermia group （bladder temperture 37 ℃） and hypothermia group （bladder temperure 28 ℃ ）. Anesthesia and surgery time, anesthetics dosage, recovery time ,liquid and blood infusion volume and blood glucose concentration were recorded. [ Results] Two groups have the similar fentanyl and pancuronium dosage , but the midazolam dosage in hypothermia group is more than that in normothermia group （P 〈 0.05）. The cases of automatic heart recover rates in normothersia group is higher than that in hypothermia group. Low cardial output rates in normothermia group is lower than that in hypothermia group （ P 〈 0.05）. Blood glucose concentration of two groups from the beginning of CPB to 3 hours in ICU is much higher than that in pre - anesthesia, and during CPB, at the ending time of CPB and surgery ,and 3 hours later to ICU , the blood glucose concentration in hypothermia group is much higher than that in normothemia group （P 〈 0.05）. The dosage of insulin in hypothermia group is much more than that in normothermia group （ P 〈 0. 05）. [ Conclusion] CPB under normothermia is easy and available with shorter CPB time than hypothermia. It doesn＇t have adverse effects on heart and do little harm to other organs,avoiding the bad damage produced by low temperure to body.
出处
《大连医科大学学报》
CAS
2005年第6期450-452,共3页
Journal of Dalian Medical University
