摘要
目的研究2型糖尿病患者的早期征象,提高2型糖尿病的诊断率。方法对246例年龄(50±15)岁(多为固定患者),既往空腹血糖及餐后2h血糖正常,尿糖阴性的患者进行问卷调查,依据患者有无餐前饥饿感,心慌,伴出汗分为A、B两组,追踪观察其空腹血糖、血脂、尿酸、24h动态血压及Holter、OGTT试验,T3、T4、TSH、C肽或胰岛素(INS)水平。以出现糖尿病为终点。结果两组患者血糖异常率间差别均有显著性意义(P<0·05);两组患者高血压、高BMI、高三酰甘油血症的发生率及糖尿病家族史间差别均有显著性意义(P<0·05);两组患者昼、夜心率变异(HRV)间差别均有显著性意义(P<0·01),A组患者昼、夜心率变异间差别有显著性意义(P<0·05),B组患者昼、夜心率变异间差别无显著性意义(P>0·05)。结论交感活性增高的人易患糖尿病。
Objective To investigate the early symptoms and signs of patients with type 2 DM, and to increase the rate of diagnosis of type 2 DM. Methods 246 patients, who were aged of （50 ＋ 15 ） and normal with their fasting and 2 h postprandial blood glucose and negative urine glucose, were surveyed by questionnaires. These patients were assigned into two groups A or B, according to whether they had symptoms of hunger, palpitation and sweating before taking dinners. Patients were followed in 7 years to observe their fasting blood glucose, blood lipids, uric acid, 24 h ambulatory blood pressure monitoring, Holter, OGTF, T3 , T4, TSH, C peptide and insulin levels. The endpoint of the observation of each patient was the occurrence of diabetes. Results There were significant differences in the abnormity rate of blood glucose between two groups （ P 〈 0, 05 ）. There were significant differences in the rate of hypertension, high BMI, hypertriglyceridemia, and family history of DM between two groups （ P 〈 0. 05 ）. There were significant differences in the HRV in day or night between two groups （ P 〈 0. 05 ）. Conclusion People with the sympathetic activity increase are easy to get DM.
出处
《中国全科医学》
CAS
CSCD
2005年第24期2023-2024,2026,共3页
Chinese General Practice
关键词
糖尿病
2型
早期症状
交感活性
高血压
睡眠障碍
Diabetes mellitus, type 2
Early symptoms
Sympathetic activity
Hypertension
Sleep disorders
