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探讨原发性高血压患者脉压与微量白蛋白尿和动脉粥样硬化的关系 被引量:2

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摘要 目的:探讨原发性高血压(EH)患者脉压(PP)与早期肾损害指标微量白蛋白尿(MAU)和动脉粥样硬化的早期征象颈动脉内膜中层厚度(C-IMT)之间的关系。方法:116名EH患者根据PP水平分为3组,对3组的MAU、C-IMT;斑块发生率、血清超敏C反应蛋白(hs-CRP)、血尿素氮(BUN)、肌酐(Cr)、尿酸(UA)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、血糖(FBG)、体重指数(BMl)等进行分析和比较。结果:1.PP≥60mmHg组的原发性高血压患者MAU水平及C-IMT明显高于PP<40mmHg组和40mmHg≤PP<60mmHg组的原发性高血压患者(P<0.05)。2.即≥60mmHg组的原发性高血压患者患者颈动脉斑块发生率明显高于PP<40mmHg组和40mmHg≤PP<60mmHg组的原发性高血压患者(P<0.05)。3.C-IMT与MAU水平呈正相关(P<0.05)。结论:原发性高血压患者脉压与尿微量白蛋白水平及颈动脉内膜中层厚度密切相关,尿微量白蛋白也是亚临床期动脉粥样硬化的早期标志。
出处 《新疆医学》 2010年第8期23-26,共4页 Xinjiang Medical Journal
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共引文献31

同被引文献23

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