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无痛性准分子激光角膜上皮瓣下磨镶术及微型角膜刀准分子激光角膜上皮瓣下磨镶术的临床研究 被引量:34

The clinical study of the epithelial flap of painless LASEK and Epi-LASIK
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摘要 目的探讨准分子激光角膜上皮瓣下磨镶术(LASEK)及微型角膜刀准分子激光角膜上皮瓣下磨镶术(Epi-LASIK)后无痛的原因及保护角膜上皮瓣的方法.方法 LASEK患者285例(285只眼), Epi-LASIK患者39例(39只眼)入选统计分析.准分子激光仪包括Mel 80、lasersight LSX、NIDEK EC5000及VISX 4star准分子仪、视可佳AOV、博士伦217Z准分子激光仪.手术由同一手术医师完成.Epi-LASIK以12点为基蒂作角膜上皮瓣.LASEK采用20%乙醇浸润10~20 s.观察术后无痛比率.结果术后疼痛:LASEK组基本无痛且术后2 d可自然睁眼的为269例(91.23%).Epi-LASIK组基本无痛且术后2 d可自然睁眼的为36例(92.31%).LASEK组与Epi-LASIK组的无痛比率都较高,差异无统计学意义.LASEK组有10例(3.51%)延期取镜,最晚11 d取.Epi-LASIK组有2例(5.13%)延期取镜,最晚10 d取.两组延期取镜的主要原因是由于角膜上皮不规则水肿.结论本研究中92%以上的LASEK及Epi-LASIK患眼术后无疼痛及刺激,有效视力的恢复迅速,接近LASIK.角膜上皮瓣延迟愈合时,推迟取接触镜是安全有效的措施.(中华眼科杂志,2005,41:977-980) Objective To protect epithelial flap and improve the rate of painless LASEK and Epi- LASIK surgery. Methods 285 eyes of 285 cases of LASEK, 39 eyes of 39 cases of Epi-LASIK were involved in the study. Laser machines used in the study included Mel 80, lasersight LSX, NIDEK ECS000, VISX 4star, AOV (66 vision) and 217Z. The Epi-LASIK hinge position was routinely at 11-12 o'clock. The application time of alcohol for LASEK was 10-20 seconds. The hinge was routinely at 12-1 o'clock by the way of epithelial-CCC. Results Postoperative pain: 269 cases (91.23%)in LASEK and 36 cases (92. 31% )in Epi-LASIK were quiet (patients did not complain pain and open the eyes in a nature way), There was no significant difference in the ration of postoperative pain between two groups. LASEK : CLs were taken off in 10 cases(3. 51% )in 7-11 days. Epi-LASIK: CLs were taken off in 2 cases(5. 13% ) in 7-10 days. The main reason of delayed taking of the CLs was irregular edema of epithelium. Conclusions The LASEK and Epi-LASIK are able to be a painless procedure. LASEK / Epi-LASIK can get quiet situation postoperatively with quickly recovery of effective vision by LASIK. Delayed taking off CLs is safe and effective to protect the survival epithelium in case of the epithelial flap delayed healing.
出处 《中华眼科杂志》 CAS CSCD 北大核心 2005年第11期977-980,共4页 Chinese Journal of Ophthalmology
关键词 角膜切削术 上皮下 激光 角膜 疼痛 视敏度 Keratectomy, subepithelial,laser-assisted Cornea Pain Visual actuity
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参考文献6

  • 1Lee JB, Seong GJ, Lee JH, et al.Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia. J Cataract Refract Surg, 2001,27:565-570. 被引量:1
  • 2Litwak S, Zadok D, Garcia-de Quevedo V, et al. Laser-assisted subepithelial keratectomy versus photorefractive keratectomy for the correction of myopia. J Cataract Refract Surg, 2002,28:1330-1333. 被引量:1
  • 3Taneri S, Zieske JD, Azar DT. Evolution, Techniques, clinical outcomes, and pathophysiology of LASEK: Review of the literature. Surv Ophthalmol,49:576-699. 被引量:1
  • 4Pallikaris IG, Kalyvianaki MI, Katsanevaki VJ, et al.Epi-LASIK: preliminary clinical results of an alternative surface ablation procedure.J Cataract Refract Surg, 2005,31:879-885. 被引量:1
  • 5周行涛,吴良成,戴锦晖,褚仁远.准分子激光上皮瓣下角膜磨镶术的角膜上皮瓣异常[J].中华眼科杂志,2002,38(2):69-71. 被引量:67
  • 6Pallikaris IG, Naoumidi II, Kalyvianaki MI. Epi-LASIK: comparative histological evaluation of mechanical and alcohol-assisted epithelial separation.J Cataract Refract Surg, 2003, 29:1496-1501. 被引量:1

二级参考文献4

  • 1Azar DT,Ang RT,Lee JB,et al.Laser subepithelial keratomileusis:electron microscopy and visual outcomes of flap photorefractive keratectomy[].Current Opinion in Ophthalmology.2001 被引量:1
  • 2Lee JB,Seong GJ,Lee JH,et al.Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia[].Journal of Cataract and Refractive Surgery.2001 被引量:1
  • 3Kornilovsky IM.Clinical results after subepithelial photorefractive keratectomy (LASEK)[].Journal of Refractive Surgery.2001 被引量:1
  • 4Scerrati E.Laser in situ keratomileusis vs.laser epithelial keratomileusis(LASIK vs. LASEK)[].Journal of Refractive Surgery.2001 被引量:1

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