摘要
A capillary GC method with headspace was established for determination of residual organic solvents——ethanol, propanone, dichloromethane, chloroform and pyridine in clindamycin phosphate. A DB-624 capillary column wasused with water as the solvent. The average recoveries of the five solvents were 98.2%, 96.7%, 98.6%, 97.5% and 103.1%,respectively. The detection limits were 7.8, 3.8, 0.4, 0.6 and 2.0μg/ml, respectively.
A capillary GC method with headspace was established for determination of residual organic solvents——ethanol, propanone, dichloromethane, chloroform and pyridine in clindamycin phosphate. A DB-624 capillary column was used with water as the solvent. The average recoveries of the five solvents were 98.2%, 96.7%, 98.6%, 97.5 %and 103.1%, respectively. The detection limits were 7.8, 3.8, 0.4, 0.6 and 2.0μg/ml, respectively.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2005年第11期705-706,共2页
Chinese Journal of Pharmaceuticals
