摘要
本文采用正交设计法，研究了离子缔合物种类，活性物在膜相中的浓度及增塑剂三因素对电极性能的影响，研制了稳定性和重现性良好的氟哌酸石墨内导PVC膜电极。电极的线性响应范围为10－2～105mol／L；检测下限可达2．5×10－6mol／L。电极直接用于胶囊含量测定，平均回收率99.36％，相对标准偏差0.85％。与药典法比较，结果基本一致。
The influences of various ionic complexes, concentration of activator in membrane phase and plasticizer on the properties of electrode were studied by orthogonal design. A PVC membrane electrode of graphite inner-conductive norfloxacin which had good stability and reproducibility was prepared. The linear response range of the electrode was 10-2~10-5 mol/L. The minimal detection limit was 2. 5×10-6 mol/L. The electrode could be used directly to analyze capsulated samples. The average recovery was 99. 36% with a RSD of 0. 85%. The results are in good agreement with those obtained by the method in pharma copeia.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
1996年第3期308-311,共4页
Chinese Journal of Analytical Chemistry
关键词
氟哌酸
聚氯乙烯
膜电极
离子选择电极
Norfloxacin, polyvinyl chloride membrane electrode, ion selective electrode
