摘要
目的探讨常规放疗剂量和照射面积与急性放射性肺炎发病率的关系及其治疗效果.方法回顾性分析1996年12月～2001年12月183例肺癌于我科常规放射治疗情况,放射剂量均为每次2 Gy,1 /d,每周5次,总剂量为50～70 Gy.结果 19例发生急性放射性肺炎,发病率为10.4%;其中照射55 Gy以下、55～65 Gy、65 Gy以上的急性放射性肺炎的发病率分别为6%、8.7%、15.6%;平均照射面积120 cm2以下、120 cm2以上的急性放射性肺炎的发病率分别为8.54%、11.88%.本组肺炎经治疗的缓解率为84.21%(16/19).结论急性放射肺炎的发病率随常规照射剂量和照射面积的增大而增加.经合理治疗可获得明显的症状及体征缓解,但应以预防为主.
Objective To analyse retrospectively the influence of irradiation dose and area on the incidence of acute radiation pneumonitis and the therapeutic efficacy of acute radiation pneumonitis in the conventional radiotherapy. Methods From December 1996 to December 2001, 183 patients with lung cancer were treated with conventional radiotherapy. The dose was 2 Gy/fraction, 1 fraction/day, 5 days/week, accumulated dose was 50-70 Gy. Results The incidence of acute radiation pneumonitis was 10. 4%. The incidences in patients recieved irradiation doses of 55 Gy below, 55-65 Gy and 65 Gy above were 6%,8. 7% and 15. 6% respectively. The incidences for patients with irradiation area of 120 cme below and 120 cme above were 8.45% and 11.88% respectively. The remission rate of acute radiation pneumonitis was 84. 21% （16/19） after therapy. Conclusion The incidence of acute radiation pneumonitis increases along with the irradiation dose and area in the conventional radiotherapy. Acute radiation pneumonitis may get obvious remission by reasonable treatments.
出处
《海军总医院学报》
2005年第3期154-155,共2页
Journal of Naval General Hospital of PLA
关键词
常规放疗
急性放射性肺炎
Conventional radiotherapy
Acute radiation pneumonitis
