摘要
目的:探讨高同型半胱氨酸血症与冠心病(CHD)中医证型的关系。方法:将60例入选的 CHD 患者按中医辨证分为气虚血瘀证、痰阻心脉证、气阴两虚证三型,采用高效液相色谱仪和荧光检测仪测定 CHD 患者与正常健康人血浆同型半胱氨酸(Hcy)水平,并对各证型 Hcy 进行比较。结果:CHD 患者 Hcy 水平高于正常健康人(P<0.05),而气虚血瘀型患者血浆 Hcy 水平高于痰阻心脉和气阴两虚型(均 P<0.01)。结论:血浆 Hcy 的异常增高是冠心病的一个危险因素,也是气虚血瘀证的主要血液理化特性之一。
Objective： To probe into relation between homocysteinemia and TCM syndrome types in the patient of coronary heart disease （CHD）. Methods： 60 cases of CHD were divided into following 3 syndromes： Qi-deficiency and blood stasis, stagnation of phlegm in heart vessels, deficiency of both Qi and Yin. Plasma hemotypic cysteine （Hcy） level in the patient of CHD and the normal person were detected with high pressure liquid chromatagraphy and fluorescent detector, and Hcy level of the various syndrome types was compared. Results： Hcy level in the patient of CHD was higher than that in the normal person （P〈0. 01）, and in the patient with Qi-deficiency and blood stasis was higher than those in the patient with stagnation of phlegm in heart vessels and the patient with deficiency of both Qi and Yin （P〈0.01）. Conclusion： Abnormal increase of plasma Hcy level is a risk factor of CHD, and is also one of important physicochemical characteristics of blood for Qi-deficiency and blood stasis syndrome.
出处
《中医杂志》
CSCD
北大核心
2005年第10期775-776,共2页
Journal of Traditional Chinese Medicine
基金
广西自然科学基金(桂科自0229046)
