摘要
目的:制备复方黄芪胶囊并建立其质量控制方法。方法:采用薄层色谱法定性鉴别方中主药西洋参和山茱萸;采用高效液相色谱-蒸发光散射法测定主药黄芪中黄芪甲苷的含量。结果:薄层定性条件适合,斑点清晰;黄芪甲苷检测线性范围为2.8μg～8.4μg(r=0.9999),平均回收率为99.93%,RSD=1.17%。结论:该制剂制备工艺简单,质量稳定,定量控制方法简便、准确,精密度高。
OBJECTIVE： To prepare compound astragali capsules and to establish its quality control standards. METHODS： The qualitation identification of the principal agents like American ginseng and asiatic cornelian cherry fruit were determined by TLC; the principal agent astragaloside Ⅰ in the astragali were identified by HPLC- ELSD. RESULTS： The condition for TLC qualitation was feasible and the spots were clear; good linear relationship was achieved when the detection concentration of astragaloside Ⅰ was within the range of 2.8μg-8.4μg（r = 0.9 999）; the average recovery was 99.93% , RSD = 1.17% . CONCLUSION： The preparing technique of this preparation was simple and the quality was stable, the quan- titation control method is simple, accurate and with high precision.
出处
《中国药房》
CAS
CSCD
北大核心
2005年第19期1469-1470,共2页
China Pharmacy
