摘要
目的观察高氧液对颅脑损伤后血流动力学的影响,评价其用于颅脑外伤急性期的治疗价值。方法对符合重型颅脑损伤诊断标准的患者60例,接受高氧液(1000ml/d,静脉输注)2周,在治疗前和治疗2周后进行血流动力学测定比较。结果经过2周的高氧液治疗,全血粘度、血浆粘度显著降低,反映红细胞变形能力的TK值减少,血沉减慢,反映红细胞聚集性的红细胞电泳指数明显增大(P<0·05),红细胞压积有减少趋势,但无显著性差异(P>0·05)。结论早期使用高氧液可降低血液粘度,改善微循环,有助于改善脑组织缺血缺氧,减轻脑水肿。
Objective To investigate the effects of hyperoxia liquid on hemorrheology in severe brain trauma, and evaluate its therapeutic value in the acute stage of severe brain injury.Methods According to Glasgow coma score （GCS） scales, 60 severe brain trauma cases （GCS≤） were selected and admitted intravenous hyperoxia liquid （1000ml/day） for two weeks. Hemorrheology was mensurated before treated and two weeks later. Results Two wecks later, whole blood viscosity （BV）, plasma viscosity （PV） reduced obviously, also the TK that expose the red blood cell deformability, HCT seem to he reduced, but without obviously variety. Conclusion Early application of hyperoxia liquid can improve mierocirculation, and decrease brain anoxia and brain edema.
