摘要
目的观察丹参注射液对原发性肾病综合征患者凝血系统的改善作用。方法将原发性肾病综合征患者42例随机分为两组:在使用足量强的松及肾病综合征常规治疗的基础上,治疗(观察)组用丹参注射液30mL加入低分子右旋糖酐250mL中静滴,1次/d,对照组以低分子右旋糖酐250mL+海普宁(低分子肝素)5000u/次静滴,1次/d,分别于用药前和用药14d后观察凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原定量(FIB)、凝血酶时间(TT)等指标变化。结果治疗后两组患者的各项指标较治疗前差异均有显著性的改善,用低右+丹参注射液疗效与使用低右+海普宁疗效差异无显著性。结论低右+丹参注射液具有和低右+海普宁相似的作用,能显著改善肾病综合征患者的高凝状态,提高肾病综合征的疗效。
[Objective] To observe the effect of Injection Salviac mittiorrhizae on coagulative system in treating patients Nephotic Syndrome. [Medthed] 42 cases of using enough and conrentimal treatment of Nephotic decided ramomlyh into two groups on the bases of using enough an conrentimal treatment of Nephotic syndrome, the patients of the treatment group were treated by intravenous drip infusing Saluiac Mittionhizac united 250 mL dextram 40, once a day, and the control troup by 5000 u heparin united 250 mL dextran 40 obseive the changes of the grideline suthas PT. APTT. FIB. tit befue brentment and after 14 days. [Results] There are great impovement in every guideline of the two groups after treatment. The effects has no significant difference between the two groups. [ Conclusion] The teatment by injection salviac Mittiorrhizac united dextram 40 has obvious anticoagulative action as by heparin united dextram 40 has, They all could improve the hyperxoagulability state in the patients.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2005年第18期2842-2844,共3页
China Journal of Modern Medicine
关键词
丹参注射液
肾病综合征
高凝状态
salviac miltiorrhizac injection
primary nephotic syndrome
coagulatlve system
