期刊文献+

通心络胶囊治疗X综合征的研究 被引量:3

Study of Tongxinluo capsule on X syndrome
下载PDF
导出
摘要 目的观察通心络胶囊治疗心脏X综合征的疗效。方法选择30例心脏X综合征患者,在给予β受体阻滞剂、钙通道阻滞剂或长效硝酸酯类药物治疗的基础上加服通心络胶囊,3粒/次,每天3次。随访12周后观察胸痛发作情况,复查平板运动试验及冠状动脉造影。结果用药后胸痛发作次数由用药前的(2.6±2.9)次/d减少为用药后的(1.3±1.5)次/d(P<0.05),平板运动试验阳性患者减少(P<0.01),平板运动试验到达终点时间明显延长(P<0.01),冠状动脉造影示冠脉血流改善(P<0.01)。结论通心络胶囊能改善血管内皮功能,提高冠状动脉血流储备及运动耐量,减少心绞痛的发作。 Objective It is to observe the curative effect of Tongxinluo capsule on cardiac X syndrome, Methods 30 patients with cardiac X syndrome were chosen and given Tongxinluo capsule 3 pills one time and 3 times a day on the base of treatment which included β- receptor blockers, calcium channel blockers or long acting nitrates. The chest pain paroxysm condition was observed and the treadmill test and coronary angiography were rechecked after following up for 12 weeks. Results After treatment, paroxysm times of chest pain were reduced from (2.6 ± 2.9) times a day before treatment to (1.3 ± 1.5 ) times a day ( P 〈 0.05), the positive cases of treadmill test decreased ( P 〈 0.01 ) , the arriving terminus time of treadmill test prolonged obviously (P 〈 0.O1 ) and coronary angiography showed coronary flow was improved (P 〈 0.01 ). Conclusion Tongxinluo capsulc can improve vascellum endothelial function, enhance coronary flow reserve and exercise tolerance and reduce the paroxysm of chest pain.
出处 《现代中西医结合杂志》 CAS 2005年第20期2640-2641,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词 通心络胶囊 X综合征 平板运动试验 冠状动脉造影 Tongxinluo capsule X syndrome treadmill test coronary angiography
  • 相关文献

参考文献8

  • 1肖文良,戴华,姜志安,张晓光,赵书健,耿小勇,邰炜彦.通心络胶囊对不稳定性心绞痛患者血管内皮细胞保护作用的研究[J].中华心血管病杂志,2002,30(5):268-268. 被引量:92
  • 2陈在嘉,高润霖主编..冠心病[M].北京:人民卫生出版社,2002:1280.
  • 3王洪巨,黄元伟,孙坚,朱朝晖,张磊.通心络胶囊对不稳定型心绞痛患者血管内皮功能的影响[J].中国中西医结合杂志,2003,23(8):587-589. 被引量:67
  • 4Gibson CM,Cannon CP,Daley WL,et al. For the TIMI 4 Study Group. TIMI frame count:a quantitative method of assessing coronary artery flow[J]. Circulation,1996,93:879-888. 被引量:1
  • 5Maseri A,Buchthal SD,Pohost GM. Chest pain and normal coronary arteries[J]. N Engl J Med,2000,343:511-512. 被引量:1
  • 6Kaski JC,Russo G. Microvascular angina in patients with syndrome X[J]. Z Kardiol,2000,89(suppl 9):121-125. 被引量:1
  • 7Yamamoto S,James TN,Kawamura K,et al. Cadiocytic apoptosis and capillary endothelial swelling as morphological evidence of myocadial ischemia in ventricular biopsies form patients with angina and normal coronary arteriograms[J]. Coron Artery Dis,2002,13:25-35. 被引量:1
  • 8Tousoulis D,Davies GJ,Asimakopoulos G,et al. Vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 serum level in patients with chest pain and normal coronary arteries(syndrome X)[J]. Clin Cardiol,2001,24:301-304. 被引量:1

二级参考文献10

共引文献152

同被引文献56

引证文献3

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部