摘要
目的观察中医药分期论治对荷瘤小鼠的治疗作用及对生存期的影响。方法将昆明种小鼠除正常组外,接种H22瘤株,制备肝癌模型,并随机分为模型组、西药组、非阶段组和阶段组。西药组予喃氟啶(FT207),非阶段组予自拟肿瘤基本方,阶段组根据不同治则予肿瘤分阶段处方。观察各组对荷瘤小鼠生长的影响。结果模型组小鼠生存期最短,阶段组生存期最长,而西药组与非阶段组生存期非常接近。结论荷瘤小鼠经不同治法分阶段治疗后其生存期呈现延长的趋势。
Objective To observe the development of H22-tumor-bearing mice in different treatment stages. Methods The mice are injected with H22 to induce liver cancer, and then randomized into model group and FF-207 group and non-phase group and different-phase group. The mice of model group drank tap water every day; the mice of FF-207 group were given FF-207 every day; the mice of non-phase group were given JIBEN prescription every day; the mice of different-phase group were administered different prescriptions on different phases. We observed the effects of the development of H22 bearing mice in different groups. Results The research showed that the life span of mice in model group was shortest; the life span in different-phase group are longest; at the same time, the life span in FF-207 group and non-phase group are similar. Conclusion The life span of mice with tumor in phases group are prolonged by different-phase herbal prescriptions.
出处
《上海中医药大学学报》
CAS
2005年第3期31-33,共3页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
国家中医药管理局中医基础理论重点学科基金资助项目
上海市教委科研基金资助项目(02CK09)
关键词
分期论治
荷瘤小鼠
肝癌
生存期
中医药疗法
Treatment by stage
tumor-hearing mouse
liver cancer
life span
Chinese medicine
