摘要
目的:观察罗格列酮联合二甲双胍治疗2型糖尿病的临床疗效。方法:64例符合2型糖尿病诊断的门诊患者随机分为:治疗组32例,应用罗格列酮4mg/次,1日1次;二甲双胍片0.25mg/次,1日3次。对照组32例服用二甲双胍片0.5mg/次,1日3次。疗程均为6周。结果:治疗组患者餐前血糖及餐后2小时血糖与其进入临床观察前不同,差异有显著性P<0.05。对照组则无此变化,P>0.05。结论:罗格列酮与二甲双胍合用治疗2型糖尿病疗效明显比单用二甲双胍为好。
Objective:To observe the curative effect of rosiglitazone combined with mefformin in the treatment of type 2 diabetes. Methods:64 outpatients corresponding to type 2 diabetes were divided into two groups at random,with 32 cases in each group.The treatment group (group A) was treated with rosigilitazone tablets 4 mg orally once a day and mefformin tablets 0.25 g three times a day,while the control group (group B) with mefformin tablets 0.5g three times a day.The course of treatment in both groups was six weeks.Results:In group A,the blood glucose of the patients was changed before meal and two hours after meal compared with that of the patients before clinical observation,with significant difference(P〈0.05).However, there was no any change im group B(P〉0.05).Conclusion:The curative effect of rosiglitazone combined with melformin is far better than that only with mefformin in type 2 diabetes.
出处
《现代医药卫生》
2005年第18期2416-2417,共2页
Journal of Modern Medicine & Health
关键词
2型糖尿病
罗格列酮
二甲双胍
疗效
Type 2 diabetes
Rosiglitazone
Mefformin
Curative effect