摘要
系统地研究了呋喃甲酸酯与三氯乙醛的缩合反应规律，提出了路易斯酸催化该反应的机制。当呋喃甲酸酯：无水三氯乙醛：三氯化铝（摩尔比）为２：１：１时，在６０～７０℃下反应６ｈ，双分子缩合产物的收率为５３～７５％。
Lewis acid-promoted hydroxyalkylation of α-furoate with anhydrate chloral was studied systematically and the mechanism was proposed in this paper.The yields of bimolecular condensation products were about 53￣75% on condition that the reaction was carried out at 60￣70℃ for about 6.0h and α-furoates/anhydrate chloral/anhydrate aluminum chloride in a molecular ratio of 2:1:1.
出处
《合成化学》
CAS
CSCD
1996年第2期141-145,共5页
Chinese Journal of Synthetic Chemistry
