摘要
49例高血压病患者随机分成两组.A组24例采用氨氯地平合并小剂量卡托普利,B组采用氨氯地平口服.疗程均为8周.结果显示,A组和B组Ⅰ、Ⅱ期的高血压病降压总有效率分别为94.44%和65.00%(P<0.05);Ⅲ期高血压病的降压总有效率分别为83.33%和100%(P>0.05);副作用的发生率依次为4.1%和20%(P<0.05).本文结果提示,氨氯地平合并小剂量卡托普利可提高降压疗效并减少副作用.
49 patients were divided into Group A and B. 24 patients in A group weretreated with amlodiprine together with low dose captopril and 25 patients in group B were given o-ral amlodiprine alone for 8 weeks. The effective rate of lowering blood pressure in stage I and I was 94. 44% in group A and 65. 00% in group B (P<0. 05). The effective rate of lowering blood pressure in stage I was 83. 33% in group A and 100% in group B (P>0. 05). The incidence of adverse effects was 4. 1% in group A and 20% in group B (P<0. 05). Our results suggest that amlodiprine together with captopril could increase the effect of reducing blood pressure and reduce the side effects of the drug.
出处
《药物流行病学杂志》
CAS
1995年第4期206-207,共2页
Chinese Journal of Pharmacoepidemiology
