摘要
通过对β-TCP陶瓷的生物相容性研究,证明材料在生物体内不会产生全身或局部毒性反应、不致溶血、不引起炎性和排斥反应,不致突变,有利于骨组织迅速长入材料孔内并与材料紧密结合;对β-TCP陶瓷的组成、常规理化性能及动物试验,证明材料具有与人体骨相近的组成,可诱发新骨生成.具有良好的生物降解性,适于作为骨修补和替代材料。
Through biocompatibility studing.of β-Ca3(PO4)2(β-TCP) ceramic,it is proved that the material don't causes all over the body or local toxicity response,hemdysis,inflammation and exclusion response,and mutation,which is benefit for bone tissue rapidly grow into those pores of the material and integrate with the material tightly. The studies of composition,routine phyicochemical properties and animal test prove that the material has a chemical composition similar to human bone, can induce new bone growth, has g good biodegradation. The material is suitable for repairing and replacing of human bone.
基金
国家自然基金
国家863青年基金