摘要
本实验以卵巢浆液性囊腺癌及粘液性腺腺癌ＴＩＬ细胞作为效应细胞，卵巢浆液性细胞及Ｋ５６２细胞作为靶细胞，采用单个细胞毒实验法，连续观察了效应细胞和靶细胞的结合及杀伤过程，发现ＴＩＬ杀伤Ｋ５６２细胞及新鲜分离的肿瘤细胞具有相似的形态变化过程，但是变化速度存在着差异，其中浆液性囊腺癌ＴＩＬ细胞杀伤自体肿瘤细胞形态变化最快，其次是杀伤异体同一组织类型细胞，最差的粘液性囊腺癌的ＴＩＬ细胞杀伤异体浆液性囊腺癌细胞，这有助于指导临床治疗。
serial observation was made by means of inverted microscopy on the mixtureof cultured TIL, K562 and tumor cells from patients with ovarian cancer. The authorshad observed the whole interaction between the effect cells and the target cells, andfound out same killing process of TIL on K562 and tumor cells from cancer patients,but the killing speed was different. The killing speed of TILs from serous cystadeno- carcinoma against autologous tumor cells was fast, that of TILs against all ogeneicovarian tumor cells was less fast, and that of TILs from mucinous adenocarcinomaagainst tumor cells from adenocarcimona was slow. this observation will be helpfulto clinical treatment
出处
《上海医学》
CAS
CSCD
北大核心
1995年第5期268-270,共3页
Shanghai Medical Journal
