摘要
目的研究三甲基-β-环糊精(TM-β-CD)对邻、间、对硝基苯酚(o-NP、m-NP、p-NP)同分异构体的分子识别作用。方法采用电化学方法测定硝基苯酚溶液中加入TM-β-CD前后峰电流和峰电位值,计算包合比及不同温度下的包合常数。结果TM-β-CD加入前后峰电流和峰电位值不同,三种包合物的包合比均为1∶1,303K时包合物TM-β-CD-o-NP,TM-β-CD-m-NP,TM-β-CD-p-NP的包合常数分别为:2·38×103,4·94×103,13·80×103。结论TM-β-CD对于o-NP、m-NP、p-NP表现出了不同的分子识别能力,p-NP>m-NP>o-NP,温度对包合常数有较大的影响。
Objective： To study the molecular recognition of trimethyl-β-cyclodextrin with o-, m-, p-, nitrophenol（o-NP, m-NP, p-NP） Isomer. Mothods. Electrochemistry was used to determine the current and electromotive peak forcebe fore and after adding TM-β-CD. The moral ratio and inclusion constant at different temperatures were calculated. Resuits： The number of the current and electromotive peak force before and after adding TM-β-CD was different. Three moral ratios are all 1 ： 1. Inclusion constants of TM-β-CD-p-NP, TM-β-CD-m-NP, TM-β-CD-o-NP are： 2.38× 10^3, 4.94 ×10^3, 13.80 × 10^3 . Conclusion： The inclusion ability of TM-β-CD to nitrophenol isomers is different： p-NP〉m-NP〉o-NP. The effect of temperature on the inclusion constant is large.
出处
《泰山医学院学报》
CAS
2005年第2期117-119,共3页
Journal of Taishan Medical College
关键词
三甲基-β-环糊精
硝基苯酚
分子识别
电化学法
trimethyl-β-cyclodextrin
nitrophenol
molecular recognition
electrochemistry method
