摘要
本文应用电生学方法观察了不同浓度的花椒浸液对蟾蜍离体神经干 A、C 两类纤维动作电位幅度和传导速度的影响。结果表明:花椒浸液对 A、C 两类纤维动作电位幅度和传导速度均有明显的抑制效应。而且随着花椒浸液浓度的增高,两类纤维动作电位幅度明显下降(P<0.01),动作电位消失时间明显缩短(P<0.01)。动作电位幅度和传导速度与花椒浸液作用时间呈显著负相关(r=-0.901～-0.977,P<0.01)。在同一时间内给予花椒浸液,C 类纤维动作电位先被阻断,然后 A 类纤维动作电位被阻断。两类纤维动作电位均消失后,用标准Ringer 液(任氏液)浸泡均可再现。
Using the electro—physiological method,We observed the effect of different concentrations of bungeanum solution on the amplitude and conduction velocity of action potential of A and C fibers in isolated nerves of toad.The results indicated that the amplitude and conduction velocity of action potential in A and C fibers were evidently inhibited when four tour concentrations of bungeanum solution were exposed to the nerves.Moreover,when the concentration of bungeanum solution was incrased,the amplitude of action potential was evidently reduced in dif- ferent groups and the time of action potential was markedly shorted(p<0.01).The amplitude and conductivity of action potential were negatively related to the duration in which bungeanum solution was exposed to nerves(r=-0.901～-0.977,p<0.01).At the same time bungeanum the solution was given the action potential of C fiber was first blocked and then,the action poten- tial of A fiber.After the action potential of two fibers disappeared,it could still revive in standard Ringers solution.
关键词
花椒浸液
C类纤维
动作电位幅度
传导速度
bungeanum solution
A fiber
action potential
amplitude
conduction velocity
