摘要
本实验探讨了牛磺酸（Ｔａｕ）对小鼠脑单胺氧化酶（ＭＡＯ）活性的影响。结果发现，在Ｔａｕ以１０μｍｏｌ／Ｌ作用后，ＭＡＯ活性无明显变化。当浓度增至２０、４０、８０μｍｏｌ／Ｌ时，ＭＡＯ活性明显下降（Ｐ＜０．０５及Ｐ＜０．０１）。实验结果表明，Ｔａｕ可降低ＭＡＯ活性，从而减少多巴胺的降解。据此实验，从生化角度上解释了Ｔａｕ治疗一些神经系统疾病的机制，如帕金森病、精神抑郁症。
Taurine(Tau) is a similar to GABA. Its some effects were found on the central nervous system in these years. In this experiment, it can decrease the activity of MAO in the mice brains in 20μmol/L(P<0.05)and 40,80μmol/L(P<0.01). In this way, Tau increases the DA in the brains. This result can explain the mechanism of treatment of some nervous system disease with Tau.
出处
《哈尔滨医科大学学报》
CAS
1995年第3期214-215,共2页
Journal of Harbin Medical University
