摘要
电高辐射、超氧阴离子自由基和羟自由基都能分别引起人淋巴细胞姊妹染色单体交换（ＳＣＥ）频率增加和细胞增殖率指数降低。ＳＣＥ与增殖率指数间密切负相关。推测电离辐射的上述生物学效应正是由辐照细胞生成的超氧阴离子和羟自由基引起的。
Sister chromatid exchange (SCE) and inhibition of cell proliferation ratio index (PRI) in human lympbocytes were induced by ionizing irradiation,superoxide anions and hydroxyl radical. There was a negative relationship betweenSCE and PRI. It was suggested that those biological effects were caused by superoxide anions and hydroxyl radicals produced in irradiated cells.
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
1995年第2期65-68,共4页
Journal of Radiation Research and Radiation Processing
关键词
电离辐射
姊妹染色单体
细胞增殖率
活性氧
Ionizing irradiation
Hydroxyl radical
Superoxide anion
Sisterchromatid exchange
Cell proliferation ratio index
