摘要
对3例心尖肥厚性心肌病(AHCM)患者进行下蹲运动试验、异丙肾上腺素及普莱洛尔试验,观察各自对巨大倒置T波的影响.结果表明,3例在运动后及静滴异丙肾上腺素后巨大倒置T波均明显变浅或转直立,而在口服普莱洛尔后T波倒置明显加深.恰与冠心病患者相反.其原因可能为;(1)心肌病患者的复极由内层向外层进行,T波倒置,异丙肾上腺素增强心肌内层张力,使内层复极延迟,致复极过程由外向内扩散,T波直立,(2)AHCM属不匀称心肌肥厚,因此复极向量及对药物的反应有别于正常者.
A test of exercises and drugs ( isoprenaline or propranolol) was made on three patients with apical hyper-trophic cardiomyopathy (AHCM) to see their respective effects on giant negative T wave. The results showed that giant negative T wave in three patients became shallower or reversed to positive after cessation of exercises or iv infusion of isoprenaline. whereas it became significantly deeper after administration of propranolol. The results were just opposite to those of coronary heart disease. The reasons might be: (1) The repolarization of hypertrophic cardiomyopathy progresses from the inside layer to the outside layer to result in negative T wave. The tonus of myocardial inside layer is enhanced by iv isoprenaline to delay the repolarization of the inside layer. So course of repolarization progresses from the outside layer to the inside layer and the T wave is reversed to positive; (2) As AHCM belongs to asymmetrical hypertrophic myocardia. the vector of repolarization and reaction to drugs in AHCM differ from those of the normal.
出处
《心电学杂志》
1995年第2期76-77,共2页
Journal of Electrocardiology(China)
