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压力和张力对骨骺板软骨细胞的影响 被引量:10

Responses of the Growth Plate Chondrocytes to Compression and Distraction
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摘要 新西兰幼兔19只,在其右股骨下端安装带有拉力和压力传感器的外固定装置,向骺板近端分别施压力和张力,左侧股骨作为对照。4周后两侧股骨作长度测量和组织学检查。结果表明压力使骺板厚度全层变薄,肥大细胞数减少,骨生长表现为抑制状态。张力使骺板增殖层和肥大层厚度增加,肥大细胞数增多,骨生长活跃。机械力使骺板软骨细胞在组织学上的变化具有统计学意义。 An external fixation device composed of two forcetransducers was applied to the right distal femur epiphyseal plate in 19 white New Zealand young rabbits, and compression or distraction was applied. the left femur served as a control, Measurements of bone length and microscopic studies of the epiphyseal plate was made 4 weeks later. The restults showed that a reduction in every zone height of the growth plate after comperssion. the number of hypertrophic chondrocytes decreased, and bone growth was almost inhibited.the height of the proliferative and hypertrophic zones was increased after distraction,the number of hypertrophic chondrocytes increased. and bone growth was active. Statistieally significant correlation exsisted between mechanical forces and the growth plate chondrocytes.
出处 《中华小儿外科杂志》 CSCD 1995年第4期227-228,共2页 Chinese Journal of Pediatric Surgery
关键词 骨骺 软骨 关节 压力 张力 软骨细胞 Epiphyses Cartilage, articular
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