摘要
应用图像分析仪对大肠管状腺瘤和绒毛状腺癌进行了核形态定量分析。选用的参数有：核面积、核周长、等效核直径及核形状因子。结果表明：除核形状因子外，其余３项参数在大肠腺癌非典型增生程度分级上有意义；４个参数在大肠腺癌分型上均无意义，从这些参数值上看不出管状腺瘤和绒毛状腺癌何者更易恶变。
A nuclear morphometric study was performed on the histologic sections of 5 normal colorectal mucosa specimens, 15 villous adenomas (VA), 15 tubular adenomas (TA) and 5 grade-1 adenocarcinomas. The parameters used in this study were nuclear area (NA), nuclear perimetry (NP), form factor of nucleus (FF) and nuclear diameter of an equivalent cycle (ND). The results revealed that NA, NP and ND are objective parameters for the grading of atypical hyperplasia of adenomas, but they are not useful for the histologic classification of adenomas. On the basis of these parameters, it is difficult to predict whether the possibility of malignant change is greater in VA or in TA.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1995年第5期351-353,共3页
Chinese Journal of Clinical Oncology
