摘要
目的探讨原发性胃MALT淋巴瘤临床诊断与治疗。方法回顾性分析10a来48例原发性胃MALT淋巴瘤的诊断与治疗情况。结果术前胃镜确诊48.8%(21/43),消化道造影确诊22.6%(7/31),术后组织标本幽门螺杆菌检出阳性率45.2%(19/42);全组手术切除率87.5%(42/48);5a生存率62.7%,ⅠE期单一切除生存率60.4%,术后加用化疗和/或放疗者达87.5%。结论幽门螺杆菌感染与原发性胃MALT淋巴瘤存在关联。原发性胃MALT淋巴瘤与胃癌相比临床上无特异性,术前确诊率低,应结合消化道造影,胃镜及反复活检综合判断。外科手术切除原发灶,联合术后化疗和/或放疗是合理的。
[Objective] To investigate the methods of preoperative diagnosis and treatment of primary gastric lymphoma of mucosa-associated lymphoid tissue (MALT) type (PGL-MALT). [Methods] To analyze retrospectively the diagnosis and treatment of 48 cases of PGL-MALT. [Results] Of the patients with PGL-MALT, 45.2% (19/42) cases were Helicobacter pylori (Hp) pathogenesis positive 22.6% (7/31); and 48.8% (21/43) cases were diagnosed by preoperative gastrointestinal image and gastroscopy with biopsy, respectively. The overall resection rate for PGL-MALT was 87.5% (42/48). In 23 cases with stage ⅠE, 8 cases treated with resection alone gave a 5-year survival rate of 62.7%, and the other 15 cases treated with resection followed by chemotherapy and /or radiotherapy had a survival rate as high as 87.5%. [Conclusions] It is obvious that PGL-MALT is associated with Hp. The preoperative diagnosis rate of PGL-MALT is slow, which should be concluded by applying gastroinstestinal image, gastroscopy and repeated biopsy. The use of curative resection in combination with the post-operative chemotherapy and /or radiotherapy to treat PGL-MALT is rational.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2005年第12期1894-1896,共3页
China Journal of Modern Medicine
关键词
原发性胃MAIT淋巴瘤
幽门螺杆菌
诊断
治疗
primary gastric lymphoma/mucosa-associated lymphoid tissue helicobacter pylori
diagnosis
treatment
