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无精子症患者附性腺功能的变化

Functional change of the accessory gentital glands of patients with the azoospermia
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摘要 目的通过检测正常供精者和无精子症患者精液参数与精浆附性腺标志物,探讨无精子症患者附性腺功能的改变。方法采用精液常规、精子形态、精浆附性腺标志物分析方法,检测正常供精者和无精子症患者的精液相关指标。结果正常对照组精浆中性α—葡糖甘酶活性显著高于无精子症组。相关分析结果显示,无精子症患者组,精液量与果糖含量和酸性磷酸酶活性呈正相关,相关系数分别为(r=0.422,P<0.01)和(r=0.410,P<0.02)。结论无精子症患者除缺乏生精功能外,还同时存在不同程度的附睾功能障碍。 Objective By way of assay of seminal routine, accessory gentital glands markers about normal donors and 35 patients with azoospermia, to explore the alteration of the accessory gential gland of the patients suffering from the azoospermia. Methods The relevant parameters of semen from 32 normal donors and 35 patients with azoospermia were measured by analysis of seminal routine and accessory gentital glands markers. Results The enzyme activity of neutral α-1, 4-glucosidase in the sample with azoospermia significantly declined as compared to the control. There was a significant positive relationship between the semen volume and the concentration of fructose and the enzyme activity of acid phosphatase in seminal plasma for the azoospermia (r=0.422, P<0.01; r=0.410, P<0.02). Conclusions The patients with azoospermia have the abnormal function of epididymis as well as the absence of spermatogenesis.
出处 《海南医学》 CAS 2005年第8期52-53,共2页 Hainan Medical Journal
关键词 无精子症 果糖 中性α-葡糖甘酶 酸性磷酸酶 人类 azoospermia fructose neutral α-1 4-glucosidase acid phosphatase human
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