期刊文献+

少弱精子症与精浆附性腺标志物的相关性分析 被引量:2

Study of the relationship between oligoasthenospermia and accessory genital glands markers
原文传递
导出
摘要 目的分析少弱精子症患者精液参数与精浆附性腺标志物的相关性,探讨附性腺功能对男性生育力的影响。方法采用精液常规、精子形态、精浆附性腺标志物分析方法,检测正常供精者和门诊就诊的少弱精子症患者的精液相关指标。结果少弱精子症组正常形态精子百分数、精子穿透功能、精浆中性α-糖苷酶显著低于正常对照组。相关分析结果显示,少弱精子症患者组,精液量与精子活动率呈负相关(r=-0.415,P<0.05),精子数与形态呈正相关(r=0.393,P<0.05)。结论少弱精子症患者同时存在不同程度的附睾功能障碍,精子功能下降,精子畸形率显著升高,睾丸生精功能越低下,精子畸形发生率越高。 Objectives To verify the effect of the accessory genital gland on the male fertility. Methods The relevant seminal parameters of 32 normal donors and 35 patients with oligoasthenospermia were measured by analysis of seminal routine, sperm morphology and accessory genital glands markers. Results The percentage of normal spermatozoa, the function of sperm penetration through cervical mucus and the enzyme activity of neutral α-1,4-glu cosidase significantly declined as compared with the control. There was a significant negative relationship between the semen volume and the sperm motility for the oligoasthenospermia(r=-0.415, P<0.05), and a significant positive relationship between the sperm count and the sperm morphology(r=0.393, P<0.05). Conclusion The abnormal function of epididymis exists in the oligoasthenospermia. Sperm function for the oligoasthenospermia declines with an increase of the percentage of the abnormal sperm. The poorer the spermatogenesis function of the testis is, the higher the percentage of the abnormal sperm appears.
出处 《中国男科学杂志》 CAS CSCD 2004年第6期17-19,共3页 Chinese Journal of Andrology
关键词 少弱精子症 果糖 中性α—糖苷酶 酸性磷酸酶 精子形态 oligoasthenospermia fructose neutral a -1, 4-glucosidase acid phosphatase sperm morphology
  • 相关文献

参考文献8

  • 1熊承良等主编..人类精子学[M].武汉:湖北科学技术出版社,2002:632.
  • 2郭应禄,李宏军主编..男性不育症[M].北京:人民军医出版社,2003:417.
  • 3Lindholmer C. Survival of human spermatozoa in diffe 24:521-526 被引量:1
  • 4Lindholmer C. The importance of seminal plasma for human sperm motility. Biol Reprod 1974; 10:533-542 被引量:1
  • 5World Health Organization. WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. Fourth Edition London: Cambridge University Press 1999:71-74 被引量:1
  • 6Paulson JD, Negro-Vilar A, Lucena E. Andology (Male Fertility and Sterility). London: academic press, inc,1986:332 被引量:1
  • 7Tremblay RR, Chapdelaine P, Mailhot J. α -1, 4-Glucosidase activity in human semen: variations with number and motility of spermatozoa. Fertil Steril 1979; 31:592-594 被引量:1
  • 8世界卫生组织编国家计划生育委员会科学技术研究所译.人类精液及精-宫颈粘液相互作用实验室检验手册第三版[M].北京:科学出版社,1994.53-54. 被引量:1

同被引文献7

  • 1Huang H Y, LeeC L, Lai Y M, et al. The impact of the total motile sperm count on the success of intrauterine insemination with husband's spermatozoa[J].J Assist Reprod Genet, 1996,13:56-63. 被引量:1
  • 2David C, Miller, Brent K, et al. Processed total motile sperm count correlates with pregnancy outcome after intrauterine insemination[J]. Urology, 2002, 60: 497-501. 被引量:1
  • 3Francavilla F, Romano R, Santucci R, et al. Effect of sperm morphology and motile sperm count on the outcome of intrauterine insemination in oliozoospermia and/ or asthenozoospermia[J]. Fertil Steril, 1990,53 : 892-897. 被引量:1
  • 4Brasch J G, Rawlins R, Tarchala S, et al. The relationship between total motile sperm count and success with intrauterine insemination[J]. Eur J Obstet Gynecol, 1994,62:150-154. 被引量:1
  • 5Liu de Y, Baker H W. High frequency of defective sperm-zona pellucida interaction in oligozoospermic infertile men[J]. Hum Reprod ,2004,19 : 228-233. 被引量:1
  • 6刘群龙,蔡志明.无精及少弱精子症研究进展[J].现代诊断与治疗,2008,19(2):84-88. 被引量:7
  • 7蒲军,吴小候,唐伟,陈在贤,王德林.640例无精子症病因分析[J].重庆医科大学学报,2010,35(2):317-319. 被引量:12

引证文献2

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部