摘要
目的:探讨比较伊曲康唑胶囊与特比萘芬片治疗甲真菌病的成本-效果。方法:将临床甲真菌病患者分为A、B两组,A组82例采用伊曲康唑胶囊口服治疗,B组79例采用特比萘芬片口服治疗,应用药物经济学成本-效果分析法进行评价。结果:伊曲康唑胶囊与特比萘芬片治疗指趾甲真菌病的总有效率分别为89. 0 2 %(73/ 82 )和91 . 1 4 %(72 / 79) ;成本分别为1 0 39 92元和1 6 5 9 .6元;C E分别为1 1 . 6 8、1 8 .2 1 ;ΔC ΔE为2 92 . 3。结论:伊曲康唑胶囊具有更合理成本-效果优势。
OBJECTIVE: To evaluate cost-effectiveness of itraconazole and terbinafine in the treatment of the patients with onychomycosis. METHODS: 161 cases with onychomycosis were divided into group A and B. Group A: 82 cases, treated with itraconazole, po; Group B: 79 cases, treated with Terbinafine, po. Curative effect of these two drugs was evaluated by pharmacoeconomic cost-effectiveness analysis. RESULTS: The total effective rate of these two drugs in the treatment of finger and toe onychomycosis was 89.02% and 91.14% respectively. The cost of group A and B was 1 039.92 and 1 659.6 yuan respectively, and cost-effectiveness rate was 11.68 and 18.21 respectively, and ΔC/ΔE was 292.3. CONCLUSION: Cost-effectiveness rate of itraconazole was lower than that of terbinafine in the treatment of onychomycosis.
出处
《中国医院用药评价与分析》
2005年第3期166-167,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
