摘要
分子印迹技术是一种新型的高效分离技术,具有空间选择性识别特性。本文介绍了分子印迹技术在蛋白质大分子上的应用和发展,包括蛋白质分子印迹选用的单体和交联剂、印迹方法、印迹机理、蛋白质分子印迹技术的应用以及存在的一些问题。
Molecular imprinting technique (MIT) is a new effective separation technique , it can prepare a polymer featuring selective recognition to a certain molecular compound. Because of the stability of molecular imprinting polymer in chemically and mechanically, MIT has been applied in several fields, such as chromatography separation, solid phase extraction, biosensor and so on . With the development of MIT, proteins imprinted technique also obtains great progresses in recent years, various proteins have been successful imprinted, such as Bovine serum albumin, Hemoglobin, proteinase et al. In this paper, the application and progress on proteins imprinted technique was introduced. The types of functional monomer and cross-linking agent, methods of imprinting, mechanism of imprinting and problems of proteins imprinting in this field were discussed respectively.
出处
《化学通报》
CAS
CSCD
北大核心
2005年第7期504-509,共6页
Chemistry
基金
国家自然科学基金资助项目(20276067)
