摘要
采用高效液相色谱技术测定了孕产妇血浆、胎儿血浆和羊水儿茶酚胺（ＣＡ）。结果表明：妊娠期母血ＣＡ中肾上腺素（Ｅ）和多巴胺（ＤＡ）与非孕妇女相比差异无显著意义（Ｐ＞０．０５），而去甲肾上腺素（ＮＥ）较非孕妇女明显降低（Ｐ＜０．０５）；阴道分娩产妇ＣＡ明显高于非孕和妊娠晚期妇女（ｐ＜０．０１）。正常足月胎儿脐动脉血ＮＥ、Ｅ及ＤＡ分别较脐静脉血的ＮＥ、Ｅ及ＤＡ增高３．３、４．７和２．１倍。剖宫产儿脐动脉血ＮＥ、Ｅ明显低于正常分娩儿，ＤＡ差异无显著意义。胎儿窘迫时脐动脉血浆ＣＡ较正常分娩儿明显增加，以ＮＥ、Ｅ最明显。羊水中ＣＡ伴随妊娠的进展而增加，胎儿窘迫时明显增加，超过正常范围上限者新生儿窒息发生率为６０％。
atecholamines (CA) levels of amniotic fluid,maternal and umbilical blood were
determined byHPLC. The results showed that epinaphrine (E) anddopamine (DA) levels of
pregnancy were significantlydifferent as compared with non-pregnant women(P>0.05), where as
norepinephrine (NE) levels weresignificantly decreased (P<0.05). In vaginal delivery,CA levels
of pregnant women were significantly hight-er than those of non and late-pregnant
women(P<0.01). Plasma CA levels of umbilical artery werehigher than those of umbilical vein
(P<0.001); NEof CA was 3.3 times, E 4.7 times and DA 2.1 times.NE and E levels of umbilical
artery in cesarean sec-tion were significantly lower than those of in vaginaldelivery. In fetal
distress, plasma NE and E levels ofumbilical artery were higher significantly than thoseof the
normal fetus. CA levels of amniotic fluid in-creased with advance of gestational
weeks,significantly in fetal distress, even more than the up-per limit of 95%. The incidence of
newborn asphyxiawas about 60.0%.
出处
《中华医学杂志》
CAS
CSCD
北大核心
1994年第8期498-501,共4页
National Medical Journal of China
关键词
儿茶酚胺
妊娠
胎血
羊水
Catecholamines PregnancyFetal blood Amniotic
fluid
