摘要
目的:利用组织多普勒成像(DTI)观测房间隔缺损封堵术前、后心脏功能的变化,以评价疗效和术后恢复情况。方法:房间隔缺损封堵术患者100例,分别于术前、术后3d、3个月和6个月进行超声心动图检查,于心尖四腔切面分别取右室侧壁三尖瓣环处、右室侧壁中部、室间隔二尖瓣环处、室间隔中部、左室侧壁二尖瓣环处以及左室侧壁中部组织多普勒速度频谱,测量收缩期(S)、舒张早期(E)和舒张晚期(A)峰值速度,计算E/A比值。结果:术前右室侧壁三尖瓣环处和右室侧壁中部各参数较大,室间隔侧二尖瓣环处和室间隔中部各参数较小;术后3d右室各运动参数显著降低,室间隔和左室S和E峰显著降低,但A峰参数无统计学变化;术后3个月右室、室间隔侧各运动参数均较术前显著降低,左室侧S峰较术前降低,余参数无统计学变化;术后6个月右室侧、室间隔二尖瓣环处各运动参数均较术前显著降低,但较术后3个月有增高趋势,室间隔中部各参数较术前无显著变化,左室S峰较术前显著降低。在各时间点中所有取样点的E/A比值无显著变化。结论:DTI能准确、定量观测房间隔缺损封堵术前、后心脏功能的变化,评价封堵术的治疗效果和恢复情况。
AIM: To evaluate the treatment effect and recovering situation through observing the change of cardiac function before and after of atrial septal defect occlusion by using tissue Doppler imaging(DTI). METHODS: In 100 patients with atrial septal defect occlusion, the tissue Doppler velocity spectra on tricuspid annulus and middle part of right ventricle, mitral annulus and middle part of ventricular septum, mitral annulus and middle part of left ventricle were detected. Systolic peak velocity(S, early diastolic peak velocity (E, late diastolic peak velocity (A) and E over A ratio were measured. RESULTS: The parameters on tricuspid annulus and middle part of right ventricle were larger, and the parameters on mitral annulus of ventricular septum and middle part of left ventricle were smaller before atrial septal defect occlusion. The parameters of right ventricle and S, E of ventricular septum and left ventricle were significantly reduced, while A unchanged statistically 3 days after occlusion. The parameters of right ventricle and ventricular septum and S of left ventricle were markedly decreased, but the other parameters of left ventricle unchanged 3 months after occlusion. The parameters of right ventricle and mitral annulus of ventricular septum were significantly reduced 6 months after occlusion, however the increasing trend was found comparing with 3 month after occlusion. The parameters of middle part of left ventricle unchanged comparing with those before occlusion. S of left ventricle was reduced comparing with those before occlusion. E over A ratios on all parts in various times were kept changeless. CONCLUSION: DTI can be used to observe the change of cardiac function accurately and quantitatively before and after atrial septal defect occlusion, and evaluate treatment effect and recovering situation.
出处
《心脏杂志》
CAS
2005年第3期279-281,共3页
Chinese Heart Journal
关键词
房间隔缺损
封堵术
多普勒成像
组织
atrial septal defect
occlusion
Doppler imaging,tissue
