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脑静脉窦血栓形成的临床与治疗 被引量:4

Clinical features and therapy of cerebral venous sinus thrombosis
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摘要 目的:探讨脑静脉窦血栓形成(cerebral venous sinus thrombosis,CVST)的临床特征、影像特点及治疗。方法:分析34例脑静脉窦血栓形成病因、临床表现、影像特征及治疗。结果:本组病因依次为产褥期(58.8%)、感染(23.5%)、脱水(2.9%)、血液病(2.9%)、外伤(2.9%);头痛、恶心、呕吐为首发症状,查体视乳头水肿89.4%,癫痫发作44.1%,脑膜刺激征阳性35.3%,意识障碍26.5%,轻偏瘫5.9%,眼球突出伴活动障碍5.9%;头MRI、MRV均显示脑静脉窦血栓形成,2例行DSA检查发现双侧横窦血栓形成;本组在应用降颅压、抗感染等药物的同时,应用低分子肝素5000u,12小时一次,疗效显著,治愈25例(73.5%),好转3例,死亡6例。结论:产褥期、感染、脱水是CVST常见原因; CVST患者主要表现为高颅压症状;头MRI和MRV能清楚显示血栓形成部位;抗凝治疗是脑静脉窦血栓形成痊愈的关键。 Objective: To investingate the clinical features and imaging diagnosis of cerebral venous sinus thrombosis (CVST). Methods: 34 cases of cerebral venous sinus thrombosis were analysised. Their original disease, clinical feature, the feature of MRI&MRV in brain and therapy were studyed. Results: Their age ranged from 18 to 65 years old(mean age 28. 6). 9 were male and 25 were female. The cause of CVST was puerperium, infaction, dehydration, injury, etc. All of them had headache and sick and vomiting. 89. 4% of them had papilledema. Nearly half of them had seizure. The occuul-ded dural sinus could be seen directly by MRI and MRV. All of them accepted the anticoagulation and got a good effects. The cure rate was 73. 5%. Conclusion Current cause of CVST was purperium and infection. MRI and MRV are the imaging investingation for the diagnosis. Anticoagulation is a good method in treatment of CVST.
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出处 《脑与神经疾病杂志》 2005年第3期163-164,共2页 Journal of Brain and Nervous Diseases
关键词 脑静脉窦 血栓形成 诊断 治疗 cerebral venous sinus thrombosis diagnosis and therapy
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参考文献2

  • 1匡培根主编..神经系统疾病药物治疗学[M].北京:人民卫生出版社,2002:1332.
  • 2Horowitz M,purdy P,Unwin H,et al.treatment of dural sinus thrombosis using selective catherization and urokinase. Ann Neurol 1995,38(1):58-67. 被引量:1

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