摘要
为探讨胃癌围手术期保驾化疗的可行性及临床意义,421例胃癌手术病人随机分成2组,试验组在围手术期施行FM方案化疗3周,另一组为对照组.结果显示胃癌病人能耐受围手术期化疗,两组对比围手术期化疗未增加术后并发症及危险性.试验组与对照组根治术后病人1、3、5年生存率分别为78.2%、51.2%、34.0%及64.7%,39.7%,24.8%(P<0.05).
In order to evaluate the feasibility and clinical role of perioperative chemotherapy in patients with gastric cancer, a series of 421 cases who underwent gastrectomy were divided randomly into two groups. Patients in the trial group were given FM protocol chemotherapy during the perioperative period for 3 weeks. The results showed that the patients tolerated well the perioperative chemotherapy and no increase of postoperative complications nor jeopardy were experienced. The 1-,3-.5-year survival rates in the chemotherapy group were 78. 2% ,51. 2%,34. 0%and those in the control group were 64. 7%,39. 7%.24. 8%respective-ly(P<0. 05). There was a significant difference between the two groups.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1994年第8期604-606,共3页
Chinese Journal of Clinical Oncology
关键词
癌
围手术期
胃肿瘤
药物疗法
Stomach cancer Chemotherapy Perioperative
